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What hull-loss rate does each generation of the Boeing 737 have?
Short answer
The original 737-100/200 series has 1.8 hull losses per million flights. The Classics drop to 0.76 per million and the Next Generation to 0.18. The MAX is the exception, with 7.21 per million flights. Of the 1,144 737-100s and -200s built, just over a hundred were lost.

Rates per million flights
The hull-loss rate of the Boeing 737's original series, the -100 and -200 models, is 1.8 per million flights. The second generation, the Classics, shows a rate of 0.76 hull losses per million flights. The Next Generation models have drastically cut that figure to 0.18 per million flights. The family's black mark is the MAX, with a loss rate of 7.21 per million flights.
Total losses versus production
Just over a hundred of the family's losses corresponded to original 737-100 or 737-200 variants. Only 1,144 examples of those early models were ever built, in the 1960s. The later variants, known as the 737-300, 737-400 and 737-500, logged 49 losses. The production run of those aircraft was 1,990 units. The most recent new-generation 737s, classified as 737-6/7/8/900, have suffered only 12 total losses. Over 5,600 aircraft of that generation have been built.
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